MillipreSigma introduces the Viresolve Barrier capsule filters to its portfolio

MilliporeSigma introduces the Viresolve Barrier capsule filters to reduce the risk of bioreactor contamination. The filters are designed to remove viruses, mycoplasma and bacteria from cell culture media.

Viresolve Barrier filters are a key component of MilliporeSigma’s Viral Safety Assurance Program to mitigate the risk of viral contamination in upstream bioprocesses and minimize the potential impact on drug supply and patient safety. The Viral Safety Assurance Program takes a holistic approach to viral safety to offer solutions to prevent viruses from entering upstream processes, detect viruses in cells, raw materials and process intermediates and remove viruses in downstream processes.

“Viral contamination is a constant process threat,” says Andrew Bulpin, head of the process solutions business area at MilliporeSigma. “One viral particle has the potential to initiate a bioreactor contamination. Our new Viresolve Barrier filters reduce the risk of bioreactor contaminations that cause process downtime, costly investigations and possible drug supply disruptions that could impact patients.”

Scalable from bench through commercial manufacturing, the filters offer high flux and high capacity virus filtration to ensure productivity, without impacting cell culture performance or protein quality attributes.  Available now in sizes up to one square meter, including scalable micro filters for process development, these capsule filters are easy to implement directly in front of the bioreactor or into a media storage container.

The Viresolve Barrier filter is the latest addition to the Viresolve portfolio, to offer solutions for virus filtration in both upstream and downstream applications.

MilliporeSigma’s Process Solutions business area provides the industry’s most comprehensive portfolio of high quality products and services for biopharmaceutical manufacturing.

For more information on Viresolve Barrier capsule filters  For additional information on MilliporeSigma’s Viral Safety Assurance Program, visit

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